Free Fatty Acid Storage in Human Visceral and Subcutaneous Adipose Tissue: Role of Adipocyte Proteins
نویسندگان
چکیده
منابع مشابه
Free Fatty Acid Storage in Human Visceral and Subcutaneous Adipose Tissue
OBJECTIVE Because direct adipose tissue free fatty acid (FFA) storage may contribute to body fat distribution, we measured FFA (palmitate) storage rates and fatty acid (FA) storage enzymes/proteins in omental and abdominal subcutaneous fat. RESEARCH DESIGN AND METHODS Elective surgery patients received a bolus of [1-(14)C]palmitate followed by omental and abdominal subcutaneous fat biopsies t...
متن کاملPlasma free fatty acid storage in subcutaneous and visceral adipose tissue in postabsorptive women.
OBJECTIVE We assessed the direct (VLDL-triglycerides [VLDL-TG] independent) storage of circulating free fatty acids (FFAs) in visceral and subcutaneous fat in postabsorptive women. RESEARCH DESIGN AND METHODS Twelve women (BMI 29.6 +/- 6.6 kg/m(2)) received an identical, intravenous bolus dose of [1-(14)C]oleate followed by timed subcutaneous fat biopsies (abdominal and femoral) and then omen...
متن کاملEffects of p-chlorophenoxyisobutyrate on free fatty acid mobilization from canine subcutaneous adipose tissue in situ.
1. The mechanism whereby p-chlorophenoxyisobutyrate (CPIB) lowers plasma non-esterified fatty acid concentrations has been studied in dogs by measuring the associated changes in adipose tissue metabolism. 2. CPIB lowered arterial concentrations of non-esterified fatty acids during isoprenaline infusion by a mean value of 41%. 3. This was accompanied by a proportionate decrease (45%) in the rele...
متن کاملFatty Acid Synthesis in Human Adipose Tissue*
The concentration of enzymes required for fatty acid synthesis was considerably less in extracts prepared from human omental adipose tissue than from rat epididymal fat. Overall rates of synthesis as measured by the incorporation of radioactive precursors into fatty acids were also much lower in human adipose tissue. The most striking difference was found with citrate-1,5-W, human adipose tissu...
متن کاملAdipocyte Fatty Acid Storage Factors Enhance Subcutaneous Fat Storage in Postmenopausal Women
Increases in weight have been associated with corresponding increases in insulin resistance in postmenopausal women. Although estrogen has significant impact on body fat and body fat distribution, the cellular mechanisms that influence this process are not yet known. We measured adipose tissue fatty acid (FA) storage and FA storage factors in 12 premenopausal and 11 postmenopausal women matched...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Diabetes
سال: 2011
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db11-0219